Recent Advances in Improving the Bioavailability of Hydrophobic/Lipophilic Drugs and Their Delivery via Self-Emulsifying Formulations

نویسندگان

چکیده

Formulations based on emulsions for enhancing hydrophobic and lipophilic drug delivery its bioavailability have attracted a lot of interest. As potential therapeutic agents, they are integrated with inert oils, emulsions, surfactant solubility, liposomes, etc.; delivering systems that use emulsion formations emerged as unique commercially achievable accession to override the issue less oral in connection drugs. an ideal isotropic oil mixture surfactants co-solvents, it self-emulsifies forms fine water when acquainted aqueous material. droplets rapidly pass through stomach, promotes vast spread all over GI (gastrointestinal tract) conquers slow disintegration commonly seen solid forms. The current status advancement technologies carrying has promulgated expansion innovative carriers controlled release self-emulsifying pellets, tablets, capsules, microspheres, etc., which got boost usage self-emulsification. present review article includes various kinds formulations size particles excipients utilized formation mechanisms increase lipophilic/hydrophobic drugs time.

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ژورنال

عنوان ژورنال: Colloids and interfaces

سال: 2023

ISSN: ['2504-5377']

DOI: https://doi.org/10.3390/colloids7010016